Biochemical Reagent
- BA3459 MB710Summary: MB710, an aminobenzothiazole derivative, is a stabilizer of the oncogenic p53 mutant Y220C.
- BA3460 MI-773Summary: MI-773 is a potent protein-protein interaction (PPI) inhibitor with high binding affinity for specific (K=8.2nM).
- BA3461 BrigimadlinSummary: Brigimadlin (BI907828) is an orally active E3 ubiquitin protein ligase inhibitor that prevents MDM-2 from negatively regulating the tumor suppressor p53.
- BA3462 P53R3Summary: P53R3 is a potent, sequence-specific DNA binding that restores p53 hotspot mutants, including p53, p53 and p53.
- BA3463 MD-222Summary: MD-222 is a first-of-its-kind, highly effective degradation agent.
- BA3464 PK11007Summary: PK11007 is a mild thiol alkylating agent with anticancer activity.
- BA3466 MDM2-IN-1Summary: MDM2-IN-1 is a synthetic interaction inhibitor.
- BA3467 MRT00033659Summary: MRT00033659 is a potent broad-spectrum kinase inhibitor.
- BA3468 RO-5963Summary: A dual inhibitor.
- BA3469 PK9327Summary: PK9327 is a small molecule stabilizer.