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Tyrosine Kinase

A8322 Neratinib (HKI-272)
3 Citation

Target: EGFR

Summary: HER2/EGFR inhibitor,potent and irreversible

insoluble in H2O; ≥13.93 mg/mL
A8252 Nintedanib (BIBF 1120)
3 Citation

Target: VEGFR|PDGFR|FGFR

Summary: VEGFR/PDGFR/FGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
A8319 Dacomitinib (PF299804, PF299)

Target: ErbB

Summary: HER inhibitor

≥23.5 mg/mL
A8245 Sorafenib Tosylate
1 Citation

Target: Raf|VEGFR

Summary: Raf kinases and tyrosine kinases inhibitor

≥31.85 mg/mL
A8247 Afatinib (BIBW2992)
1 Citation

Target: EGFR

Summary: Irreversible EGFR/HER2 inhibitor

≥24.3 mg/mL
A8234 Erlotinib Hydrochloride
2 Citation

Summary: Selective EGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥6.44 mg/mL
A8237 SKLB610

Summary: Potent VEGFR inhibitor

insoluble in H2O; ≥20.75 mg/mL
A8219 Gefitinib (ZD1839)
15 Citation

Target: EGFR

Summary: Selective EGFR inhibitor

≥22.34 mg/mL
A8236 Regorafenib
4 Citation

Target: Raf|VEGFR|PDGFR|c-Kit|RET

Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1

≥25.04 mg/mL
A8218 Lapatinib
7 Citation

Target: ErbB

Summary: EGFR/HER2 inhibitor,potent,selective and reversible

≥29.05 mg/mL