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Bioactive Compounds
Signaling Pathways
Metabolic Enzyme/Protease

Metabolic Enzyme/Protease

B8217 PKM2 inhibitor(compound 3k)

Summary: A potent, selective PKM2 inhibitor

≥34.5 mg/mL
B8201 Sivelestat sodium tetrahydrate

Soluble in DMSO
B7960 Vadadustat

Summary: HIF-PH inhibitor

insoluble in H2O; ≥57.7 mg/mL
B7945 Urolithin A

≥22.8 mg/mL
B7943 2-Arachidonoyl Glycerol

Summary: Endogenous agonist of CB1 receptor and CB2 receptor

Soluble in DMSO
B7936 Flavin adenine dinucleotide disodium

Summary: Redox cofactor (electron carrier), involved in several important enzymatic reactions in metabolism

insoluble in DMSO; insoluble in EtOH; ≥207.5 mg/mL
B7932 Navoximod

Target: IDO

Summary: Orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1)

Soluble in DMSO
B7923 OSMI-1

Summary: OSMI-1 is a cell permeable inhibitor of OGT (O-GlcNAc transferase)

≥50.6 mg/mL
B7922 3-Bromopyruvic acid

Summary: HB7922exokinase II inhibitor

≥16.7 mg/mL
B7919 GSK864

Summary: Allosteric inhibitor of IDH1 mutants R132C, R132H, and R132G

Soluble in DMSO