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Topoisomerase

A3966 Doxorubicin
3 Citation

Summary: DNA topoisomerase II inhibitor

≥27.2 mg/mL
A3925 Voreloxin Hydrochloride

Summary: Antineoplastic naphthyridine analogue

Soluble in DMSO
A3924 Voreloxin

Summary: Topo II inhibitor

insoluble in H2O; insoluble in EtOH; insoluble in DMSO
A3872 TH-302

Summary: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth

≥22.45 mg/mL
A3434 Genz-644282

Summary: Non-camptothecin inhibitor of topoisomerase I

Soluble in DMSO
A3372 DOXO-EMCH

Summary: Prodrug of doxorubicin

Soluble in DMSO
A3355 Deferasirox Fe3+ chelate

Summary: Oral iron chelator

Soluble in DMSO
A3123 4'-Demethylepipodophyllotoxin

Summary: Anti-cancer drug

≥83.33 mg/mL
A2877 Camptothecin
5 Citation

Target: Topoisomerases

Summary: Topoisomerase I inhibitor,prototypic

insoluble in H2O; insoluble in EtOH; ≥8.7 mg/mL
A2782 Amonafide

Summary: DNA intercalator,Topo II inhibitor

insoluble in EtOH; insoluble in H2O; ≥14.17 mg/mL