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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8446 Ibuprofen

Target: COX

Summary: inhibitor of cyclooxygenase 1 and cyclooxygenase 2

insoluble in H2O; ≥10.31 mg/mL
A8447 Imidapril HCl

Target: ACE

Summary: RAAS inhibitor

insoluble in H2O; ≥16.5 mg/mL
A8448 INCB28060
2 Citation

Target: c-MET

Summary: C-Met inhibitor,ATP-competitive and novel

insoluble in EtOH; insoluble in H2O; ≥5.15 mg/mL
A8449 Indomethacin

Target: COX

Summary: Cox inhibitor
A8453 Isradipine (Dynacirc)

Summary: Calcium channel blocker

≥12.55 mg/mL
A8454 Istradefylline (KW-6002)

Target: Adenosine A2A Receptors

Summary: Selective A2A receptor antagonist

insoluble in H2O; insoluble in EtOH; ≥8.78 mg/mL
A8455 Nilvadipine

Summary: Calcium channel inhibitor

insoluble in H2O; ≥12.4 mg/mL
A8456 JTC-801

Target: NOP Receptors

Summary: KOR-3 (NOP) receptor antagonist

≥22.4 mg/mL
A8458 Lamivudine

Target: HBV Proteases

Summary: Nucleoside analog reverse transcriptase inhibitor

≥10.5 mg/mL
A8459 Laquinimod (ABR-215062)

Summary: Immunomodulator,orally-available,quinolinone-based and broad spectrum

insoluble in H2O; ≥17.25 mg/mL