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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A2838 OSI-930

Summary: Inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck

≥22.15 mg/mL
A1748 Ramelteon
1 Citation

Target: Melatonin Receptors

Summary: Agonist of melatonin receptor(M1-M2),highly selective

insoluble in H2O; ≥12.95 mg/mL
A1835 Pelitinib (EKB-569)

Summary: EGFR inhibitor,potent and irreversible

insoluble in EtOH; insoluble in H2O; ≥11.7 mg/mL
A2986 ADL5859 HCl

Summary: δ-opioid receptor agonist,selective

≥21.45 mg/mL
A5118 BTZ043 Racemate
2 Citation

Target: DprE

Summary: DprE1 inhibitor

insoluble in H2O; ≥10.4 mg/mL
A2150 Andarine

Target: Androgen Receptors

Summary: Androgen receptor agonist

≥21 mg/mL
A2174 Lenvatinib (E7080)

Target: VEGFR|PDGFR|RET

Summary: VEGFR inhibitor

≥21.35 mg/mL
A1404 Rigosertib sodium salt
1 Citation

Target: PLK

Summary: Plk1 inhibitor

≥23.65 mg/mL
A1186 AMG-208

Summary: C-Met inhibitor,potent and highly selective

insoluble in EtOH; insoluble in H2O; ≥3.83 mg/mL
A1393 WZ8040

Target: EGFR

Summary: EGFR T790M inhibitor,irreversible amd potent

≥24.05 mg/mL