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Bioactive Compounds

Bioactive Compounds

A4013 Aspirin (Acetylsalicylic acid)

Summary: Cyclooxygenase (COX) inhibitor
A4090 JNJ-26481585
3 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
A4062 KW-2478

Target: HSP90

Summary: Potent Hsp90 inhibitor, novel, non-ansamycin,

≥100 mg/mL
A4077 Dabigatran

Summary: A potent, reversible direct thrombin inhibitor with core bioactivity of inhibiting thrombus formation.

insoluble in DMSO; insoluble in EtOH; insoluble in H2O
A4157 Iniparib (BSI-201)

Summary: PARP1 inhibitor,intravenously adminsitered

insoluble in H2O; ≥103.4 mg/mL
A2606 Epoxomicin
35 Citation

Summary: proteasome inhibitor

≥27.73 mg/mL
A4038 Alogliptin (SYR-322)
1 Citation

Target: DPP-4

Summary: DPP-4 inhibitor,potent and highly selective
A4114 MLN8054

Target: Aurora Kinases

Summary: Aurora A inhibitor

insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
A4211 Lenalidomide (CC-5013)

Target: angiogenesis

Summary: Antineoplastic agent,inhibits angiogenesis

insoluble in EtOH; insoluble in H2O; ≥100.8 mg/mL
A4206 Pifithrin-α (PFTα)
6 Citation

Target: p53

Summary: p53 inhibitor

insoluble in H2O; ≥17.45 mg/mL