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Bioactive Compounds

Bioactive Compounds

A4171 EPZ005687
2 Citation

Target: EZH2

Summary: EZH2 inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
A4040 Atazanavir sulfate (BMS-232632-05)

Summary: Protease inhibitor

≥28.7 mg/mL
A4115 JNJ-7706621
1 Citation

Target: Cyclin-Dependent Kinases|Aurora Kinases

Summary: Potent CDK/Aurora kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
A4208 NSC 319726

Target: p53

Summary: Reactivator of mutant p53
A4212 Pomalidomide (CC-4047)

Summary: Immunomodulator,antumor/anti-angiogenic

insoluble in EtOH; insoluble in H2O; ≥7.5 mg/mL
A4237 Amuvatinib (MP-470, HPK 56)

Summary: Tyrosine kinase inhibitor

≥22.4 mg/mL
A2612 MG-115
1 Citation

Target: Proteasome

Summary: Potent reversible proteasome inhibitor

≥23.08 mg/mL
A4303 GSK3787

Summary: PPARβ/δ antagonist,novel and irreversible

insoluble in H2O; ≥15.8 mg/mL
A4323 Vardenafil HCl Trihydrate

Target: Phosphodiesterases (PDEs)

Summary: PDE5 inhibitor, potent and selective

≥13.3 mg/mL
A4341 Apixaban

Summary: Factor Xa inhibitor