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Bioactive Compounds

Bioactive Compounds

A5700 BS-181 HCl

Target: Cyclin-Dependent Kinases

Summary: CDK7 inhibitor,highly selective

insoluble in H2O; ≥20.85 mg/mL
A5803 BIX 02188

Target: MEK

Summary: MEK5 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL
A8317 Fludarabine Phosphate (Fludara)
2 Citation

Target: STAT

Summary: Inhibits STAT1 activation and DNA synthesis

insoluble in EtOH; ≥17.6 mg/mL
A8449 Indomethacin

Target: COX

Summary: Cox inhibitor
A8397 Chlorothiazide

Target: Carbonic Anhydrases

Summary: Carbonic anhydrase inhibitor

insoluble in H2O; insoluble in EtOH; ≥14.85 mg/mL
A8554 Dapivirine (TMC120)

Target: Reverse Transcriptases

Summary: Nonnucleoside reverse transcriptase inhibitor

insoluble in H2O; ≥13.5 mg/mL
A8633 Concanamycin A
9 Citation

Target: Vacuolar-type ATPase

Summary: V-type (vacuolar) H+-ATPase inhibitor

soluble in DMSO
B3062 CW069

Summary: allosteric inhibitor of HSET, selective

≥50 mg/mL
B1582 MM-102
1 Citation

Summary: MLL1 inhibitor,high-affinity peptidomimetic
B1439 Golvatinib (E7050)

Target: VEGFR

Summary: C-Met/VEGFR-2 inhibitor