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Bioactive Compounds

Bioactive Compounds

A4453 NSC 687852 (b-AP15)

Target: Deubiquitinating enzymes (DUBs)

Summary: 19S regulatory particle Inhibitor

insoluble in EtOH; insoluble in H2O; ≥20.95 mg/mL
A4484 PRIMA-1MET

Summary: Restore mutant p53 activity, induce BAX and PUMA
A3963 A-769662
4 Citation

Summary: AMPK activator,potent and reversible

insoluble in EtOH; insoluble in H2O; ≥18.02 mg/mL
A8253 PD 173074
5 Citation

Target: VEGFR|FGFR

Summary: FGFR inhibitor

≥26.18 mg/mL
A5057 MGCD-265

Target: VEGFR|c-MET

Summary: Met/Flt/Flk/Ron/Tie-2 inhibitor

≥25.9 mg/mL
A5449 PIK-93

Summary: PI3Kγ/PI4KIIIβ/PI3Kα inhibitor

insoluble in H2O; ≥19.5 mg/mL
A5455 AEE788 (NVP-AEE788)

Summary: EGFR/HER-2/VEGFR inhibitor

≥22.05 mg/mL
A5511 Ofloxacin

Target: Topoisomerases|DNA gyrase

Summary: Fluoroquinolones,antibiotics

insoluble in H2O; insoluble in EtOH; ≥12.03 mg/mL
A5719 AT7519

Target: Cyclin-Dependent Kinases

Summary: Multi-CDK inhibitor
A1947 MEK162 (ARRY-162, ARRY-438162)

Target: MEK

Summary: MEK1/2 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; insoluble in DMSO