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Bioactive Compounds

Bioactive Compounds

A8807 MK-8745

Target: Aurora Kinases

Summary: Aurora A inhibitor,potent and selective

≥21.6 mg/mL
B1525 SSR128129E

Summary: allosteric inhibitor of FGFR1, orally-active

insoluble in EtOH; insoluble in H2O; ≥17.3 mg/mL
B3249 Vanoxerine

Summary: potent and selective DRI (Dopamine reuptake inhibitor)

Soluble in DMSO
B3255 Meisoindigo

Summary: Apoptosis inducer;potential agent for AML

insoluble in H2O; insoluble in EtOH; ≥25.85 mg/mL
B1163 MK-4827 hydrochloride

Summary: PARP1/PARP2 inhibitor

≥23.7 mg/mL
B5802 ICA 121431

Summary: human NaV1.3 and NaV1.1 channels inhibitor

Soluble in DMSO
B8001 GNE-477

Summary: dual PI3K/mTOR inhibitor

insoluble in H2O; insoluble in EtOH; ≥16.69 mg/mL
B5873 Spautin-1
1 Citation

Target: Deubiquitinating enzymes (DUBs)|Autophagy

Summary: Novel autophagy inhibitor

insoluble in H2O; ≥13.5 mg/mL
B5888 Retigabine

Summary: An activator of voltage-gated potassium channel, used as an anticonvulsant agent
B5913 C7280948

Summary: Novel PRMT1 inhibitor

insoluble in H2O; insoluble in EtOH; ≥13.9 mg/mL