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Bioactive Compounds

Bioactive Compounds

B1251 Valproic acid
6 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC1 inhibitor

≥12.35 mg/mL
B5347 SC 58125

Summary: COX-2 inhibitor

Soluble in DMSO
B4492 HS-173

Target: PI3K

Summary: novel PI3K inhibitor

≥21.1 mg/mL
B4754 LDC000067
2 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK9 inhibitor, novel and highly specific

insoluble in H2O; insoluble in EtOH; ≥18.52 mg/mL
B4976 Desogestrel

Summary: progestin used in hormonal contraceptives

insoluble in H2O; ≥13.7 mg/mL
B5835 AZD2932

Target: FLT3|VEGFR|PDGFR|c-Kit

Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit

Soluble in DMSO
B5875 E3330

Summary: Ape-1/Ref-1 inhibitor

insoluble in H2O; ≥75.4 mg/mL
B5889 EGF816
2 Citation

Target: EGFR

Summary: Novel covalent inhibitor of mutant-selective EGFR

Soluble in DMSO
C3503 MS023 (hydrochloride)

Summary: type I PRMTs inhibitor

≤30 mg/mL
C4711 AM6545

Summary: CB1 selective neutral antagonist

≤10 mg/mL