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Bioactive Compounds

Bioactive Compounds

A1174 AMG-517

Target: TRP Channel

Summary: TRPV1 antagonist,potent and highly selective

≥21.5 mg/mL
A1387 AZD5363
6 Citation

Target: Akt

Summary: AKT inhibitor,pyrrolopyrimidine derived

≥21.45 mg/mL
A1929 Macitentan

Summary: Endothelin (ET)(A) and ET(B) receptor antagonist

≥24.4 mg/mL
A2005 Nutlin-3b

Target: p53-MDM2 interaction

Summary: MDM2/p53 inhibitor
A1769 KU-0060648
1 Citation

Target: PI3K|DNA-PK

Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
A2664 VX-661
2 Citation

Target: CFTR

Summary: F508del CFTR corrector

≥21.8 mg/mL
A1720 Duvelisib (IPI-145, INK1197)

Target: PI3K

Summary: PI3K-δ/PI3K-γ inhibitor

≥20.84 mg/mL
A8306 MOG (35-55)
5 Citation

Summary: Minor component of CNS myelin

≥32.25 mg/mL
A8372 AZ3146

Summary: Mps1 inhibitor,potent and selective
A8430 Ezetimibe
1 Citation

Target: Cholesterol absorption

Summary: Cholesterol transport inhibitor

≥20.45 mg/mL