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Bioactive Compounds

Bioactive Compounds

A4167 SGC 0946

Summary: DOT1L inhibitor,highly potent and selective

≥30.95 mg/mL
A4199 Sabutoclax

3 Citation

Target: Bcl-2|Mcl-1|Bfl-1

Summary: pan-Bcl-2 inhibitor

insoluble in H2O; ≥205.6 mg/mL
A4300 GW9662

7 Citation

Summary: PPARγ antagonist

insoluble in H2O; ≥13.75 mg/mL
A4317 Apremilast (CC-10004)

1 Citation

Target: Phosphodiesterases (PDEs)

Summary: PDE4 inhibitor

≥23.05 mg/mL
A4326 TAK-700 (Orteronel)

3 Citation

Target: human lyase

Summary: Human 17,20-lyase inhibitor

insoluble in H2O; ≥11.2 mg/mL
A4342 Gimeracil

Summary: Dihydropyrimidine dehydrogenase inhibitor
A1922 Z-VDVAD-FMK

3 Citation

Summary: Caspase-2 inhibitor

≥34.8 mg/mL
A3157 Alosetron

Summary: 5-HT3 receptor antagonist

Soluble in DMSO
A3266 BS-181

Target: Cyclin-Dependent Kinases

Summary: CDK7 inhibitor,highly selective

Soluble in DMSO
A3322 Cobimetinib (racemate)

Summary: Selective MEK inhibitor

Soluble in DMSO