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Bioactive Compounds

Bioactive Compounds

B4984 MI-77301 (SAR405838)

Summary: orally available MDM2 antagonist

≥17.2 mg/mL
B5856 GSK1349572 sodiuM salt

Summary: Next-generation HIV integrase (IN) inhibitor

insoluble in H2O; insoluble in EtOH; ≥8.06 mg/mL
B5880 CCT244747

Target: Chk

Summary: Potent and selective CHK1 inhibitor

Soluble in DMSO
B5925 ELN441958

Summary: Potent and selective bradykinin B1 receptor antagonist

Soluble in DMSO
A8452 ODM-201

Target: Androgen Receptors

Summary: new-generation androgen receptor inhibitor
B5999 FLLL32

Summary: STAT3 inhibitor
B6004 PX-478 2HCl

7 Citation

Target: Hypoxia Inducible Factors (HIFs)

Summary: HIF-1α inhibitor

≥19.7 mg/mL
B6020 GSK621

1 Citation

Target: AMPK

Summary: AMPK agonist

insoluble in H2O; insoluble in EtOH; ≥28.5 mg/mL
A8721 CBR-5884

1 Citation

Target: 3-phosphoglycerate dehydrogenase

Summary: selective inhibitor of PHGDH

insoluble in EtOH; insoluble in H2O; ≥16.8 mg/mL
B1012 MS436

Target: Bromodomains

Summary: BRD4 inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.15 mg/mL