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Bioactive Compounds

Bioactive Compounds

A4064 NVP-BEP800

Target: HSP90

Summary: Oral Hsp90β inhibitor, novel, fully synthetic
A4070 Elvitegravir (GS-9137)

Target: HIV Integrases

Summary: HIV-1 integrase inhibitor,potent

insoluble in H2O; insoluble in EtOH; ≥20.35 mg/mL
A4159 PJ34 hydrochloride

Summary: PARP inhibitor,potent and cell-permeable

insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL
A8205 Atazanavir
1 Citation

Summary: HIV protease inhibitor,highly potent

≥28.6 mg/mL
A4116 Danusertib (PHA-739358)
2 Citation

Target: Aurora Kinases

Summary: Pan-aurora kinase inhibitor

≥23.75 mg/mL
A4210 Bay 11-7821 (BAY 11-7082)
14 Citation

Summary: IKK/NF-κB/TNFα inhibitor

insoluble in H2O; ≥64 mg/mL
A4216 Thalidomide

Target: Ubiquitin E3 Ligases

Summary: Immunomodulatory agent,sedative drug,angiogenesis inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.8 mg/mL
A4228 Nutlin-3

Target: MDM2

Summary: MDM2 antagonist,inhibits MDM2-p53 interaction

≥58.2 mg/mL
A2614 Bortezomib (PS-341)
58 Citation

Target: Proteasome

Summary: proteasome inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.21 mg/mL
A4304 Rosiglitazone
7 Citation

Summary: Potent PPARγ agonist

insoluble in EtOH; insoluble in H2O; ≥17.85 mg/mL