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Bioactive Compounds

Bioactive Compounds

A4209 NSC 207895 (XI-006)

Target: MDMX

Summary: MDMX inhibitor,anti-cancer agent
A4213 Necrostatin-1
34 Citation

Target: RIP kinases

Summary: RIP1 inhibitor

insoluble in H2O; ≥12.97 mg/mL
A4224 GDC-0152
2 Citation

Target: Inhibitor of apoptosis proteins (IAP)

Summary: IAP antagonist,potent amd samll-molecule

≥24.95 mg/mL
A4202 RITA (NSC 652287)

Summary: Mdm2-p53 interaction and p53 ubiquitination blocking

insoluble in H2O; ≥14.6 mg/mL
A4194 Obatoclax mesylate (GX15-070)
1 Citation

Target: Bcl-2

Summary: Potent Bcl-2 inhibitor

insoluble in H2O; ≥20.7 mg/mL
A8202 Abiraterone acetate

Target: Cytochrome P450 (CYP450)

Summary: Cytochrome p450 17a1 inhibitor

insoluble in H2O; ≥11.22 mg/mL
A4186 Bromosporine
1 Citation

Target: Bromodomains

Summary: Bromodomain inhibitor,non-selective

≥40.4 mg/mL
A8389 Carbenoxolone disodium
1 Citation

Target: Gap Junctions

Summary: 11β-HSD inhibitor

≥30.74 mg/mL
A8422 Emtricitabine
1 Citation

Target: Reverse Transcriptases

Summary: Reverse transcriptase inhibitor

≥10.4 mg/mL
A8553 PTC124 (Ataluren)

Summary: CFTR-G542X nonsense allele inhibitor

insoluble in H2O; ≥10.6 mg/mL