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AmpalexAmpakine and nootropic

Ampalex

Catalog No. A3176
Size Price Stock Qty
10mM (in 1mL DMSO) $80.00 In stock
100mg $108.00 In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

Ampalex

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Chemical Properties

Cas No. 154235-83-3 SDF Download SDF
Synonyms CX516; BDP 12; Ampakine CX516
Chemical Name piperidin-1-yl(quinoxalin-6-yl)methanone
Canonical SMILES C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2
Formula C14H15N3O M.Wt 241.29
Solubility DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

Ampalex (Ampakine CX516) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). Ampalex ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation. Researches suggest that AMPA receptors may be potential pharmaceutical targets for the treatment of neurodegenerative diseases, and highlights AMPAkines, in particular, as possible therapeutic agents.