SLU-PP-332
SLU-PP-332 (CAS No.: 303760-60-3) is a synthetic small-molecule peptide analog designed to activate PGC-1α (peroxisome proliferator-activated receptor gamma coactivator 1-alpha), a master regulator of mitochondrial biogenesis. It functions as an agonist of nuclear receptors, targeting estrogen-related receptors (ERRα, ERRβ, and ERRγ), thereby enhancing mitochondrial function and regulating cellular respiration.
Early-stage research indicates that SLU-PP-332 may promote mitochondrial biogenesis and function, enhance physical stamina and endurance, improve glucose regulation and fatty acid oxidation, and potentially aid in neuroprotection and anti-aging pathways. In skeletal muscle cell line studies, SLU-PP-332 enhances mitochondrial function and cellular respiration, with EC₅₀ values of 98 nM for ERRα, 230 nM for ERRβ, and 430 nM for ERRγ.
Preliminary studies and anecdotal evidence suggest that SLU-PP-332 maintains high efficacy when administered orally, making it a promising candidate for non-invasive peptide therapy research.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 290.32 |
| Cas No. | 303760-60-3 |
| Formula | C18H14N2O2 |
| Solubility | ≥50.8 mg/mL in DMSO; ≥2.39 mg/mL in EtOH with gentle warming and ultrasonic; insoluble in H2O |
| Chemical Name | (E)-4-hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide |
| SDF | Download SDF |
| Canonical SMILES | O=C(C1=CC=C(O)C=C1)N/N=C/C2=CC=C3C=CC=CC3=C2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
