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Signaling Pathways

Items 11-20 of 69

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  1. Ki16425
    A1987 Ki16425
     4 Citation
    Target: LPA Receptors
    Summary: LPA receptor antagonist
      ≥23.75 mg/mL
  2. AZD7762
    A5919 AZD7762
    Target: Chk
    Summary: Checkpoint kinase inhibitor,ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥18.1 mg/mL
  3. Dynasore
    A1605 Dynasore
     4 Citation
    Target: GTPases
    Summary: Dynamin and GTPase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.12 mg/mL
  4. PF-562271
    A8310 PF-562271
     1 Citation
    Target: FAK|Pyk2
    Summary: ATP-competitive FAK inhibitor, reversible
      ≥25.35 mg/mL
  5. PF-00562271
    A8320 PF-00562271
    Target: FAK|Pyk2
    Summary: FAK/Pyk2 inhibitor,potent and ATP-competitive
      insoluble in EtOH; insoluble in H2O; ≥11.1 mg/mL
  6. KU-60019
    A8336 KU-60019
     2 Citation
    Target: ATM/ATR
    Summary: ATM kinase inhibitor,potent and selective
      ≥27.4 mg/mL
  7. PF-562271 HCl
    A8345 PF-562271 HCl
    Target: FAK|Pyk2
    Summary: FAK/Pyk2 inhibitor
      ≥26.35 mg/mL
  8. K-252c
    A8344 K-252c
    Target: PKC|PKA
    Summary: Protein kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥15.55 mg/mL
  9. AZD8931 (Sapitinib)
    A8375 AZD8931 (Sapitinib)
    Target: EGFR|ErbB
    Summary: ErbB inhibitor
      ≥23.7 mg/mL
  10. GSK1838705A
    A8440 GSK1838705A
    Target: Insulin and Insulin-like Receptors|ALK
    Summary: IGF-IR/IR/ALK inhibitor, ATP-competitive
      ≥26.65 mg/mL

Items 11-20 of 69

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Category
  1. Proteases14item
  2. Apoptosis1 item
  3. Chromatin/Epigenetics7item
  4. Metabolism1 item
  5. MAPK Signaling5item
  6. Tyrosine Kinase9item
  7. DNA Damage/DNA Repair4item
  8. PI3K/Akt/mTOR Signaling4item
  9. Cell Cycle/Checkpoint9item
  10. Ubiquitination/ Proteasome8item
  11. JAK/STAT Signaling3item
  12. TGF-β / Smad Signaling3item
  13. GPCR/G protein2item
  14. Stem Cell2item
  15. Membrane Transporter/Ion Channel5item
  16. Endocrinology and Hormones1 item
  17. Neuroscience3item
  18. Others2item
  19. Immunology/Inflammation1 item
Specificity
  1. Selective56item
  2. Non-Selective1 item
Target
  1. Caspases1 item
  2. Cyclin-Dependent Kinases2item
  3. Proteasome3item
  4. Cathepsins4item
  5. Histone Deacetylases (HDACs)2item
  6. Akt1 item
  7. PI3K2item
  8. CXCR1 item
  9. Raf1 item
  10. Aurora Kinases2item
  11. mTOR1 item
  12. MMP1 item
  13. Myosin II ATPases1 item
  14. Factor Xa1 item
  15. LPA Receptors1 item
  16. PLK1 item
  17. Chk1 item
  18. VEGFR1 item
  19. JNK1 item
  20. MEK1 item
  21. Deubiquitinating enzymes (DUBs)1 item
  22. Src1 item
  23. NMDA Receptors1 item
  24. Microtubules/Tubulins2item
  25. EGFR2item
  26. FAK3item
  27. JAK2item
  28. Syk1 item
  29. AMPK1 item
  30. S-nitrosoglutathione reductase1 item
  31. CFTR1 item
  32. thrombin1 item
  33. ErbB2item
  34. Actin1 item
  35. ERK1 item
  36. PKC1 item
  37. Calpains1 item
  38. M1 Receptors1 item
  39. SMYD21 item
  40. RAD511 item
  41. Trypsins1 item
  42. Pyk23item
  43. Voltage-gated Calcium Channels (CaV)1 item
  44. Insulin and Insulin-like Receptors1 item
  45. ALK1 item
  46. GTPases1 item
  47. CETP1 item
  48. PKA1 item
  49. Myosin light chain kinases (MLCKs)1 item
  50. MK21 item
  51. ATM/ATR1 item
  52. AChE1 item
  53. ZAP-701 item
  54. Catechol O-Methyltransferase (COMT)1 item
  55. DPP-41 item
  56. Dipeptidyl-peptidase II1 item
  57. P97 ATPase1 item
  58. Aromatases1 item
  59. UCH1 item
  60. MST1 item
  61. ATM1 item
Reported Experiments
  1. Animal Experiments58item
  2. Cell Experiments37item
Related Disease
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  2. Acute Myeloid Leukemia1 item
  3. Breast Cancer10item
  4. Cancer30item
  5. Colon Cancer3item
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  7. Diabetes1 item
  8. Glioblastoma1 item
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  11. Hypercholesterolemia1 item
  12. Inflammatory Diseases2item
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  15. Lymphoma1 item
  16. Mantle Cell Lymphoma1 item
  17. Multiple Myeloma1 item
  18. Pancreatic Cancer4item
  19. Prostate Cancer1 item
  20. Psoriasis1 item
  21. Renal Cancer2item
  22. Rheumatoid Arthritis1 item