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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8712 MCB-613

Target: Src

Summary: stimulator of steroid receptor coactivator (SRC)

insoluble in H2O; ≥13.2 mg/mL
B5815 LY2584702

Target: p70 rsk

Summary: p70 S6 kinase inhibitor

≥22.25 mg/mL
B5816 PLX647

Summary: dual inhibitor of FMS and KIT kinases
B5817 GDC-0994
2 Citation

Summary: ERK1/2 inhibitor

≥44.1 mg/mL
B5818 GSK2838232

Summary: HIV-1 maturation inhibitor

Soluble in DMSO
B5820 RO5126766(CH5126766)

Summary: Raf/MEK dual inhibitor

insoluble in H2O; insoluble in EtOH; ≥35.7 mg/mL
B5822 TMC647055 Choline salt

Summary: inhibitor of the hepatitis C virus NS5B polymerase

insoluble in H2O; insoluble in EtOH; ≥72.8 mg/mL
B5823 LP533401 hcl

Target: Tph

Summary: Tph-1 inhibitor

≥56.3 mg/mL
B5830 G007-LK
1 Citation

Summary: tankyrase 1/2 inhibitor

≥26.5 mg/mL
B5831 Acalisib (GS-9820)

Target: PI3K

Summary: PI3Kδ inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL