Palbociclib
Catalog No.
BA3750
Palbociclib (PD0332991) is an orally active and selective inhibitor.
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Palbociclib (PD0332991) is an orally active and selective inhibitor.Palbociclib exhibits antiproliferative activity against cancer cells and induces cell cycle arrest in them, and can be used in HR-positive and HER2-negative breast cancers, as well as in studies related to hepatocellular carcinoma.
- 1. Pimchanok Menapree, Nattaya Duangthim, et al. "CDK4/6 inhibitors upregulate cIAP1/2, and Smac mimetic LCL161 enhances their antitumor effects in cholangiocarcinoma cells." Sci Rep.2025 Feb 25;15(1):6826. PMID: 40000765
- 2. Vivian I Ko, Kailee Ong, et al. "CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation." Neurobiol Dis. 2024 Jun 15:196:106516. PMID: 38677657
| Physical Appearance | A solid |
| Storage | 4°C, protect from light |
| M.Wt | 447.53 |
| Cas No. | 571190-30-2 |
| Formula | C24H29N7O2 |
| Synonyms | PD 0332991 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |