IGF-II, human recombinant
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family. IGF-II have a much higher growth-promoting activity than insulin and binds to the tyrosine kinase type I receptor (IGF-IR) and the IGF-II/Mannose-6-phosphate receptor. IGF-II expression is influenced by placenta lactogen.
Human IGF-II is synthesized as two precursor isoforms with N- and alternate C-terminal propeptides, which are proteolyzed to produce the identical 7.5 kDa mature IGF-II. Mature IGF-II is highly conserved between the human, bovine and porcine proteins (100% identity), and exhibits cross-species activity. Recombinant Human IGF-II is a 7.5 kDa protein containing 67 amino acid residues.
|Determined by competitive binding against plasma-derived IGF-II to human placental membranes.|
|ED50||< 1.0 ng/ml.|
|Specific activity||> 1*106 units/mg.|
Quality Control & DataSheet
- View current batch:
Purity: ≥98%, by SDS-PAGE and HPLC.
Endotoxin Level:< 0.1 ng/μg
Related Biological Data
Related Biological Data
|Gene ID:||3481||Accession #:||P01344|
|Alternate Names:||Human IGF-II, IGF-II, IGFII, IGFII, IGF2, IGF-2, IGF 2, h-IGF-II, rh-IGF-II, recombinant human IGF-II, recombinant IGF-II, IGF.|
|Source:||Escherichia Coli.||M.Wt:||7.5 kDa|
|Appearance:||Lyophilized protein||Storage:||Store at -20°C|
|Formulation:||Lyophilized with no additives.|
|Solubility:||Reconstitute in 10 mM acetic acid to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.|
|Shipping Condition:||Gel pack.||Handling:||Centrifuge the vial prior to opening.|
|Usage:||For Research Use Only! Not to be used in humans.|