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Caspase-1, mouse recombinant protein

Catalog No.
E1010
Caspase-1, expressed in E. coli, suitable for cell culture.
Grouped product items
SizePriceStock Qty
25 units
$221.00
Ship with 10-15 days
100 units
$372.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

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Background

Caspase-1 belongs to the caspase-family of cysteine proteases. Caspase-1 exists in cells as an inactive proenzyme. The molecular mass of the proenzyme is 45 kDa. Caspase-1 is expressed as a zymogen that is cleaved into p20 (20 kDa) and p10 (10 kDa) subunits that become part of the active enzyme. Caspase-1 has been revealed to induce cell necrosis or pyroptosis. The studies implicated caspase-1 in promoting CD4 T-cell death and inflammation by HIV, two signature events that fuel HIV disease progression to AIDS. The recombinant active mouse caspase-1 was expressed in E. coli.

Description

Gene ID: 12362 Accession #: P29452
Alternate Names:Active Mouse Caspase-1, Caspase-1 Enzyme, caspase-1, mouse caspase-1, mouse caspases, active caspases, caspase-1 assay positive control.
Source: Escherichia Coli. M.Wt: large (20 kD) and small (10 kD) subunits.
Appearance: Semi-Dry Storage: Store at -70℃
Formulation:Lyophilized
Solubility:Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Shipping Condition: Dry Ice. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: N/A
    Endotoxin Level:N/A