Signaling pathways
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BA5505 JHU37160Summary: JHU37160 is a potent and permeable agonist across the blood-brain barrier. - BA5506 AceclidineSummary: Aceclidine (Quinuclidin-3-ylacetate) is a modulator and agonist of the M3 muscarinic acetylcholine receptor (EC:40 μM).
- BA5507 VU0467485Summary: VU0467485 (AZ13713945) is a potent, selective, orally bioavailable muscarinic acetylcholine receptor 4 orthosteric modulator (PAM).
- BA5508 FustinSummary: Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β inhibitor.
- BA5509 RevefenacinSummary: Revefenacin (TD-4208; GSK1160724) is a potent antagonist.
- BA5510 TalsaclidineSummary: Talsaclidine is a muscarinic agonist with preferential neurostimulatory properties.
- BA5511 CycrimineSummary: Cycrimine is an orally active muscarinic cholinergic receptor antagonist that reduces acetylcholine levels in a Parkinson's model.
- BA5513 JHU37152Summary: JHU37152 is a potent and permeable agonist across the blood-brain barrier.
- BA5514 ML375Summary: ML375 (VU0483253) is a potent, highly selective, blood-brain-barrier-crossing and orally active negative-alteration modulator (NAM) with M5's of 300 nM and 790 nM for human and rat, respectively.
- BA5515 ArborineSummary: Inhibits the peripheral effects of acetylcholine and induces a fall in blood pressure.