Signaling pathways
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BA8910 Dyrk1A-IN-5Summary: Dyrk1A-IN-5 is a potent and selective inhibitor. -
BA8911 Dyrk1A-IN-4Summary: Dyrk1A-IN-4 is a potent inhibitor with oral activity.
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BA8912 Dyrk1A-IN-3Summary: Dyrk1A-IN-3 is a highly selective bispecific tyrosine-regulated kinase 1A inhibitor that binds DYRK1A with high affinity (=76nM).
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BA8913 BT173Summary: BT173 is a potent homologous structural domain interacting protein kinase 2 (HIPK2) inhibitor.
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BA8914 FINDYSummary: FINDY is a folding intermediate selective inhibitor of DYRK1A.
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BA8915 ALW-II-49-7Summary: ALW-II-49-7 is a selective inhibitor.
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BA8916 123C4Summary: 123C4 is a potent, selective, competitive receptor tyrosine kinase agonist.
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BA8917 UniPR129Summary: UniPR129 was a potent antagonist (=0.84-3.01 μM).
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BA8918 JI-101Summary: JI-101 is an orally active multi-targeted kinase inhibitor with anticancer activity.
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BA8919 TargefrinSummary: Targefrin is an effective targeted agent that acts as an antagonist.