Signaling pathways
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BA8492 IbiglustatSummary: Ibiglustat (Venglustat) is an orally active, blood-brain barrier-crossing inhibitor of glucose ceramide synthetase. -
BA8493 SinbaglustatSummary: Sinbaglustat (OGT2378) is a dual inhibitor of glucose ceramide synthetase and non-lysosomal glucose ceramidase. - BA8494 TominersenSummary: Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets Huntingtin (HTT) mRNA and effectively inhibits HTT synthesis.
- BA8495 RovanersenSummary: Rovanersen (WVE-120101) is an antisense oligonucleotide that prevents the production of defective proteins by specifically targeting mutant mRNA copies of genes without affecting normal mRNAs of the genes.
- BA8496 FlupirtineSummary: Flupirtine (D9998) is a neuronal potassium channel opener.
- BA8497 PSB-1434Summary: PSB-1434 is a monoamine oxidase B inhibitor.
- BA8499 PXS-4728ASummary: PXS-4728A (BI-1467335) is a selective aminourea-sensitive amine oxidase inhibitor with oral activity.
- BA8501 LOX-IN-3Summary: LOX-IN-3 is an orally active lysyl oxidase inhibitor.
- BA8502 NialamideSummary: A non-selective, irreversible monoamine oxidase inhibitor (MAOI).
- BA8503 IsocarboxazidSummary: Isocarboxazid is a non-selective, irreversible monoamine oxidase inhibitor.