Signaling pathways
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BA6325 BNT411Summary: BNT411 is a selective agonist that induces IFNa release in vivo and in vitro. - BA6326 CU-CPD107Summary: CU-CPD107 is a potent selective agonist.
- BA6327 MobocertinibSummary: Mobocertinib (TAK-788) is an orally effective and irreversible inhibitor.
- BA6328 PyrotinibSummary: Pyrotinib (SHR-1258) is a potent and selective dual inhibitor.
- BA6329 BLU-945Summary: BLU-945 is a potent, highly selective, reversible epidermal growth factor receptor tyrosine kinase inhibitor (TKIs) with oral activity.
- BA6330 LazertinibSummary: A potent, reversible, orally available, blood-brain barrier-crossing, mutant-selective, third-generation tyrosine kinase inhibitor.
- BA6332 TX1-85-1Summary: TX1-85-1 is an irreversible inhibitor.
- BA6333 BI-4020Summary: BI-4020 is a fourth generation, orally active, non-covalent tyrosine kinase inhibitor.
- BA6334 MavelertinibSummary: Mavelertinib is a selective, orally effective and irreversible tyrosine kinase inhibitor with values of 5, 4, 12 and 3 nM for Del, L858R and double mutant T790M/L858R and T790M/Del, respectively.
- BA6335 PF-06459988Summary: PF-06459988 is an orally active, irreversible and mutant-selective mutant inhibitor.