MS9427
Catalog No.
BA6378
MS9427 was an effective degrader with 7.1 nM and 4.3 nM for wild-type and mutant L858R, respectively.
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MS9427 is a potent degrader of wild-type and mutant L858R at 7.1 nM and 4.3 nM, respectively.MS9427 selectively degrades mutants but not WT via the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways.MS9427 has a potent inhibitory effect on the proliferation of NSCLC cells.MS9427 can be used in anticancer Research.
| Physical Appearance | A solid |
| Storage | 4°C, protect from light |
| M.Wt | 993.47 |
| Cas No. | 2772613-37-1 |
| Formula | C48H58ClFN8O12 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |