Signaling pathways
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BA5508 FustinSummary: Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β inhibitor. - BA5509 RevefenacinSummary: Revefenacin (TD-4208; GSK1160724) is a potent antagonist.
- BA5510 TalsaclidineSummary: Talsaclidine is a muscarinic agonist with preferential neurostimulatory properties.
- BA5511 CycrimineSummary: Cycrimine is an orally active muscarinic cholinergic receptor antagonist that reduces acetylcholine levels in a Parkinson's model.
- BA5513 JHU37152Summary: JHU37152 is a potent and permeable agonist across the blood-brain barrier.
- BA5514 ML375Summary: ML375 (VU0483253) is a potent, highly selective, blood-brain-barrier-crossing and orally active negative-alteration modulator (NAM) with M5's of 300 nM and 790 nM for human and rat, respectively.
- BA5515 ArborineSummary: Inhibits the peripheral effects of acetylcholine and induces a fall in blood pressure.
- BA5516 AnisodamineSummary: Anisodamine (6-Hydroxyhyoscyamine), belladonna alkaloid, is also a non-subtype-selective muscarinic and nicotinic cholinergic receptor antagonist.
- BA5517 AC260584Summary: AC260584 is a muscarinic receptor variant agonist.
- BA5518 ML381Summary: ML381 (VU0488130) is a highly selective