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Bioactive Compounds
Signaling Pathways
Ubiquitination/ Proteasome

Ubiquitination/ Proteasome

A8628 Chloroquine diphosphate
1 Citation

Target: Autophagy

Summary: Antimalarial drug, TLR7 and TLR9 inhibitor

insoluble in DMSO; insoluble in EtOH; ≥106.06 mg/mL
B3516 DUBs-IN-3

Summary: potent deubiquitinase enzyme inhibitor

Soluble in DMSO
A4010 Salinosporamide A (NPI-0052, Marizomib)

Target: Proteasome

Summary: 20S proteasome inhibitor

Soluble in DMSO
A8627 Bafilomycin A1
5 Citation

Summary: V-ATPases inhibitor

Soluble in DMSO
B3515 DUBs-IN-2

Summary: deubiquitinase enzyme inhibitor

≥17.03 mg/mL
A4009 CEP-18770
1 Citation

Summary: Proteasome inhibitor

insoluble in H2O; ≥16.75 mg/mL
A8544 Wortmannin
5 Citation

Summary: PI3K inhibitor,selective and irreversible

≥21.42 mg/mL
B1317 ML-323

Target: Deubiquitinating enzymes (DUBs)

Summary: USP1-UAF1 inhibitor
A4008 MLN2238
2 Citation

Summary: β5 site of the 20S proteasome inhibitor
A8487 Nocodazole
6 Citation

Target: Microtubules/Tubulins

Summary: microtubule polymerization inhibitor

insoluble in H2O; insoluble in EtOH; ≥15.066 mg/mL