Protein Tyrosine Kinase/RTK
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A4694 BIBF 1202Summary: A VEGFR2 kinase inhibitor for tumor angiogenesis mechanisms -
A4693 ZanubrutinibSummary: A BTK inhibitor for the treatment of mantle cell lymphoma and other B-cell malignancies -
A4691 GilteritinibSummary: A FLT3 kinase inhibitor for the treatment of acute myeloid leukemia -
A4690 PemigatinibSummary: An orally selective FGFR inhibitor for the treatment of cholangiocarcinoma -
A4687 Pexidartinib hydrochlorideSummary: An orally administered potent ATP-competitive CSF1R and c-Kit kinase inhibitor -
A4684 LarotrectinibSummary: An orally administered selective TRK-inhibiting antitumor agent -
A4683 ZipalertinibSummary: An oral kinase inhibitor that selectively targets the ATP-binding site in the EGFR hinge region -
A4651 Defactinib hydrochlorideSummary: A dose- and time-dependent inhibitor of FAK Tyr397 phosphorylation -
A4650 RepotrectinibSummary: A tyrosine kinase inhibitor for the treatment of ROS1-positive non-small cell lung cancer -
A4649 Alectinib HydrochlorideSummary: A highly selective, orally available ALK inhibitor with central nervous system penetration

