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P450

Items 11-17 of 17

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  1. (+)-Ketoconazole
    B1240 (+)-Ketoconazole
    Summary: Potent inhibitor of cytochrome P450c17
      ≥25.5 mg/mL
  2. Abiraterone acetate
    A8202 Abiraterone acetate
    Target: Cytochrome P450 (CYP450)
    Summary: Cytochrome p450 17a1 inhibitor
      insoluble in H2O; ≥11.22 mg/mL
  3. Avasimibe
    A4318 Avasimibe
    Target: Acyl coenzyme A: cholesterol acyltransferases
    Summary: ACAT inhibitor,orally bioavailable
      ≥25.09 mg/mL
  4. Ketoconazole
    A4316 Ketoconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase
      ≥23.4 mg/mL
  5. PF-4981517
    A4311 PF-4981517
    Summary: CYP3A4 inhibitor,potent and selective
      Soluble in DMSO
  6. Alizarin
    A4308 Alizarin
    Summary: Chelator for calcium,used to stain calcium deposites,Alizarin complexone is used for bone staining to study bone remodeling
      insoluble in EtOH; insoluble in H2O; ≥8.12 mg/mL
  7. Abiraterone
    A4240 Abiraterone
     1 Citation
    Summary: Potent CYP17 inhibitor
      insoluble in EtOH; insoluble in H2O; ≥5.57 mg/mL

Items 11-17 of 17

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