Metabolic Enzyme/Protease
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BA2806 SC-43Summary: SC-43, a derivative of Sorafenib, is a potent agonist with oral activity. -
BA2801 3-HydroxykynurenineSummary: 3-Hydroxykynurenine, a tryptophan metabolite, is a potential endogenous neurotoxin with elevated expression levels in several neurodegenerative diseases.
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BA2798 TM5441Summary: TM5441, an orally bioavailable inhibitor of fibrinogen activator inhibitor-1, inhibited several cancer cell lines with values ranging from 13.9 to 51.1 μM and induced intrinsic cell death in several human cancer cells. -
BA2795 1G244Summary: 1G244 was a potent inhibitor at 12 nM and 84 nM, respectively, but did not inhibit DPPIV and DPPII.
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BA2783 BTdCPUSummary: BTdCPU is a heme-regulated inhibitory kinase activator that promotes phosphorylation and induces apoptosis in (Dex)-resistant cancer cells.
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BA2782 JX06Summary: JX06 is a potent, selective, covalent inhibitor.
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BA2778 POMHEXSummary: POMHEX is a racemic mixture of POM precursor active molecules that are cell-permeable and specific inhibitors of HEX.
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BA2763 DinoprostSummary: Dinoprost (ProstaglandinF2α) is an orally effective prostaglandin F (PGF) receptor agonist. -
BA2761 KRIBB11Summary: KRIBB11 is an inhibitor. -
BA2755 MilademetanSummary: Milademetan (DS-3032) is a specific, orally active inhibitor for acute myeloid leukemia and solid tumors.