Metabolic Enzyme/Protease
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BA2845 MepazineSummary: Mepazine (Pecazine) is a potent and selective protease inhibitor. - BA2844 TMI-1Summary: TMI-1 is a potent inhibitor of deintegrin metallase 17 and other matrix metalloproteinase MMPs.
- BA2840 TomatineSummary: Tomatine is a glycoside alkaloid found in the tomato plant (Mill.).
- BA2839 NBDHEXSummary: NBDHEX is a potent inhibitor of glutathione S-transferase P1-1.
- BA2830 BufotalinSummary: Bufotalin is a steroidal lactone isolated from VenenumBufonis with potent antitumor activity.
- BA2820 HinokiflavoneSummary: Hinokiflavone, a novel modulator of splicing activity, is effective in vitro and in vivo.
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BA2815 MitoBloCK-6Summary: MitoBloCK-6 is a potent inhibitor. - BA2806 SC-43Summary: SC-43, a derivative of Sorafenib, is a potent agonist with oral activity.
- BA2801 3-HydroxykynurenineSummary: 3-Hydroxykynurenine, a tryptophan metabolite, is a potential endogenous neurotoxin with elevated expression levels in several neurodegenerative diseases.
- BA2798 TM5441Summary: TM5441, an orally bioavailable inhibitor of fibrinogen activator inhibitor-1, inhibited several cancer cell lines with values ranging from 13.9 to 51.1 μM and induced intrinsic cell death in several human cancer cells.