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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8309 Perifosine
1 Citation

Target: Akt

Summary: Akt inhibitor
A8310 PF-562271
1 Citation

Target: FAK|Pyk2

Summary: ATP-competitive FAK inhibitor, reversible

≥25.35 mg/mL
A8311 Maraviroc
2 Citation

Target: CCR

Summary: Selective CCR5 antagonist,antiretroviral agent

≥25.7 mg/mL
A8313 RAF265

Target: Raf|VEGFR

Summary: Multiple intracellular kinases inhibitor

≥25.9 mg/mL
A8314 Temsirolimus

Summary: MTOR inhibitor

≥51.5 mg/mL
A8315 NU7441 (KU-57788)
4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8316 PD 0332991 (Palbociclib) HCl
15 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor

≥14.48 mg/mL
A8317 Fludarabine Phosphate (Fludara)
2 Citation

Target: STAT

Summary: Inhibits STAT1 activation and DNA synthesis

insoluble in EtOH; ≥17.6 mg/mL
A8318 PP242

Target: mTOR

Summary: MTOR inhibitor, selective and ATP-competitive
A8319 Dacomitinib (PF299804, PF299)

Target: ErbB

Summary: HER inhibitor

≥23.5 mg/mL