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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8198 P 22077

Summary: USP7/(DUB)USP47 inhibitor

insoluble in H2O; insoluble in EtOH; ≥14.6 mg/mL
A8199 PD153035 hydrochloride
1 Citation

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; insoluble in H2O; ≥3.97 mg/mL
A3001 PCI-32765 (Ibrutinib)
7 Citation

Summary: Bruton's tyrosine kinase (BTK) inhibitor

≥22.02 mg/mL
A3002 ABT-888 (Veliparib)
6 Citation

Summary: Potent PARP inhibitor
A3003 MDV3100 (Enzalutamide)
12 Citation

Target: Androgen Receptors

Summary: androgen receptor antagonist

≥23.22 mg/mL
A3004 Vemurafenib (PLX4032, RG7204)
12 Citation

Target: Raf

Summary: BRAF kinase inhibitor

≥24.5 mg/mL
A3006 GDC-0068 (RG7440)
2 Citation

Target: Akt

Summary: Pan-AKT inhibitor,highly selective

≥22.9 mg/mL
A3009 Sorafenib
11 Citation

Target: Raf|VEGFR

Summary: Raf kinases and tyrosine kinases inhibitor

≥23.25 mg/mL
A3010 MK-2206 dihydrochloride
51 Citation

Target: Akt

Summary: Akt1/2/3 inhibitor

insoluble in EtOH; ≥12.01 mg/mL
A3012 Ruxolitinib (INCB018424)
4 Citation

Target: JAK

Summary: JAK1 and JAK2 inhibitor

insoluble in H2O; ≥15.32 mg/mL