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Bioactive Compounds

Bioactive Compounds

A2949 Linifanib (ABT-869)

Target: VEGFR|PDGFR

Summary: VEGFR/PDGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL
A2412 CP-724714

Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R

Summary: HER2 inhibitor,potent and selective

≥23.5 mg/mL
A2764 PIK-90

Summary: PI3K inhibitor,potent selective

insoluble in DMSO
A5354 Zonisamide

Target: Voltage-gated Sodium (NaV) Channels|Voltage-gated Calcium Channels (CaV)|Carbonic Anhydrases|Calcium-Activated Potassium (KCa) Channels

Summary: Antiepileptic with anticonvulsant and mechanistic effect

insoluble in H2O; ≥8.35 mg/mL
A5506 Thiazovivin

Target: ROCK

Summary: ROCK inhibitor

≥15.55 mg/mL
A5391 Varenicline Tartrate

Summary: Subtype-selective agonist of α4β2 nicotinic receptors,orally active

insoluble in EtOH; ≥18.07 mg/mL
A8302 Tenovin-6

Target: Sir2-like Family Deacetylases (Sirtuins)

Summary: SIRT inhibitor and p53 activator

≥22.75 mg/mL
A8348 LY2157299
2 Citation

Summary: TGF-βR1 inhibitor,potent and selective

insoluble in H2O; ≥18.45 mg/mL
A8349 Omecamtiv mecarbil

Target: Myosin

Summary: Cardiac myosin activator
A8343 Go 6983
5 Citation

Summary: pan-PKC inhibitor

≥22.15 mg/mL