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Bioactive Compounds

Bioactive Compounds

B2290 Beta-Lapachone

Target: Topoisomerases

Summary: DNA topoisomerase I inhibitor,selective

insoluble in H2O; ≥10.85 mg/mL
B1515 Raloxifene HCl

Target: Estrogen and Related Receptors

Summary: Estrogen receptor (ER)

≥22.35 mg/mL
A4149 S-Ruxolitinib (INCB018424)

Target: JAK

Summary: JAK1/2 inhibitor,potent and selective

≥51.8 mg/mL
A4107 Sodium Phenylbutyrate

Target: Histone Deacetylases (HDACs)

Summary: Histone deacetylase inhibitor

≥27.65 mg/mL
A4132 CCT137690

Target: Aurora Kinases

Summary: Aurora A/B/C inhibitor

insoluble in H2O; insoluble in EtOH; ≥6.89 mg/mL
B5558 AR-M 1000390 hydrochloride

Summary: Delta-opioid receptor agonist,low-internalizing

<38.49 mg/mL
B5715 NS 11021

Summary: large-conductance Ca2+-activated potassium channels activator

Soluble in DMSO
B4892 TAI-1
3 Citation

Target: Hec1

Summary: Hec1 inhibitor, potent, first-in-class

≥43.2 mg/mL
B4902 (+)-Apogossypol

Target: Bcl-2

Summary: inhibitor of Bcl-2 family proteins

insoluble in H2O; ≥16.2 mg/mL
B4948 UNC 2400

Summary: negative control of UNC1999

Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl