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Bioactive Compounds

Bioactive Compounds

A3349 Darapladib

Summary: Lp-PLA2 inhibitor, selective and orally active

≥32.95 mg/mL
A3358 Deltarasin

Target: Phosphodiesterases (PDEs)

Summary: KRAS-PDEδ interaction inhibitor

Soluble in DMSO
A3359 Desmopressin

Summary: Hemostatic and anti-diuretic

insoluble in EtOH; ≥106.4 mg/mL
A3368 DMAT
2 Citation

Target: Pim|CK2|HIPK2|HIPK3

Summary: CK2 inhibitor,potent and selective

≥23.85 mg/mL
A3369 DMP 777

Summary: Leukocyte elastase (HLE) inhibitor

Soluble in DMSO
A3374 Dronedarone

Target: Cytochrome P450 (CYP450)|sodium channel|adrenergic receptor|potassium channel|calcium channel

Summary: CYP3A4 and 2D6 inhibitor,moderate

≥27.84 mg/mL
A3375 DY131

Summary: ERRγ agonist

insoluble in H2O; ≥37.1 mg/mL
A3380 Ebrotidine

Summary: H2-receptor antagonist,competitive

Soluble in DMSO
A3387 Eltrombopag Olamine

Summary: C-mpl agonist

insoluble in EtOH; insoluble in H2O; ≥14.12 mg/mL
A3389 EMD638683
4 Citation

Target: SGK

Summary: SGK1 inhibitor

insoluble in H2O; ≥18.2 mg/mL