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Bioactive Compounds

Bioactive Compounds

A5047 Ivacaftor (VX-770)

1 Citation

Summary: Potent CFTR potentiator

insoluble in H2O; ≥19.6 mg/mL
A2324 Dexamethasone (DHAP)

12 Citation

Target: interleukin receptor

Summary: Glucocorticoidan; anti-inflammatory

insoluble in H2O; ≥19.623 mg/mL
A2174 Lenvatinib (E7080)

6 Citation

Target: VEGFR|PDGFR|RET

Summary: VEGFR inhibitor

≥21.35 mg/mL
A1393 WZ8040

Target: EGFR

Summary: EGFR T790M inhibitor,irreversible amd potent

≥24.05 mg/mL
A2278 NVP-AEW541

Target: Insulin Receptor

Summary: IGF-IR inhibitor, novel, potent and selective

≥22 mg/mL
A2080 PIK-75 HCl

Summary: Inhibitor of PI3K isoform p110α

insoluble in H2O; insoluble in EtOH; ≥8.15 mg/mL
A8019 Perindopril Erbumine

Target: Angiotensin-Converting Enzymes (ACEs)

Summary: ACE inhibitor

≥111.4 mg/mL
A5710 Tazarotene

Summary: Topical retinoid;antiproliferative;inducer of TIG3 tumor suppressor
A5275 Tenofovir

1 Citation

Summary: HIV reverse transcriptase inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.38 mg/mL
A5489 Zibotentan (ZD4054)

1 Citation

Summary: ETA receptor antagonist,potent and specific

insoluble in EtOH; insoluble in H2O; ≥7.2 mg/mL