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Bioactive Compounds

Bioactive Compounds

A4166 EPZ5676

2 Citation

Target: DOT1L

Summary: DOT1L inhibitor,potent and SAM competitive

≥28.15 mg/mL
A4111 VX-680 (MK-0457,Tozasertib)

1 Citation

Target: Aurora Kinases

Summary: Aurora kinase inhibitor

≥23.25 mg/mL
A4034 Linagliptin (BI-1356)

Summary: DDP-4 inhibitor,highly potent and competitive

insoluble in H2O; insoluble in EtOH; ≥17.85 mg/mL
A2585 MG-132

136 Citation

Target: Proteasome

Summary: proteasome inhibitor

≥23.78 mg/mL
A4051 NSC 405020

1 Citation

Target: MMP

Summary: MT1-MMP inhibitor

insoluble in H2O; ≥11.4 mg/mL
A4209 NSC 207895 (XI-006)

Target: MDMX

Summary: MDMX inhibitor,anti-cancer agent
A4213 Necrostatin-1

35 Citation

Target: RIP kinases

Summary: RIP1 inhibitor

insoluble in H2O; ≥12.97 mg/mL
A4224 GDC-0152

2 Citation

Target: Inhibitor of apoptosis proteins (IAP)

Summary: IAP antagonist,potent amd samll-molecule

≥24.95 mg/mL
A4202 RITA (NSC 652287)

Summary: Mdm2-p53 interaction and p53 ubiquitination blocking

insoluble in H2O; ≥14.6 mg/mL
A4194 Obatoclax mesylate (GX15-070)

1 Citation

Target: Bcl-2

Summary: Potent Bcl-2 inhibitor

insoluble in H2O; ≥20.7 mg/mL