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Bioactive Compounds

Bioactive Compounds

A2890 Nepafenac

Summary: COX-1 and COX-2 inhibitor

insoluble in EtOH; insoluble in H2O; ≥9.95 mg/mL
A2846 OSU-03012 (AR-12)
1 Citation

Target: PDK-1

Summary: Potent PDK1 inhibitor

≥23 mg/mL
A1670 Enzastaurin (LY317615)
2 Citation

Target: PKC

Summary: PKC beta inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
A1196 SGX-523
1 Citation

Target: MET

Summary: MET inibitor, highly selective, ATP-competitive

≥17.95 mg/mL
A2168 Dovitinib (TKI-258, CHIR-258)
2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
A1767 Entecavir Hydrate

Summary: Antiviral drug used in hepatitis B infection

insoluble in EtOH; insoluble in H2O; ≥9.7 mg/mL
A1379 Nelarabine

Summary: Prodrug of ara-G for T-LBL/T-ALL

insoluble in EtOH; ≥14.85 mg/mL
A2838 OSI-930

Summary: Inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck

≥22.15 mg/mL
A2150 Andarine

Target: Androgen Receptors

Summary: Androgen receptor agonist

≥21 mg/mL
A1684 Aprepitant

Target: Substance P/NK1 Receptor

Summary: Substance P (SP) inhibitor

≥26.72 mg/mL