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Bioactive Compounds

Bioactive Compounds

B2133 Suprofen

Target: COX

Summary: dual COX-1/COX-2 inhibitor

insoluble in H2O; ≥82.8 mg/mL
B2208 Ramipril

Summary: angiotensin-converting enzyme (ACE) inhibitor

insoluble in H2O; ≥17.55 mg/mL
B1591 Ki16198

Target: LPA Receptors

Summary: LPA antagonist
B2288 Pirfenidone

Summary: TGF-β production inhibitor
B1630 VU 0361737

Summary: MGlu4 receptor allosteric modulator

Soluble in DMSO
B2200 Esomeprazole Magnesium

Summary: Proton pump inhibitor
A3018 Trametinib (GSK1120212)
30 Citation

Target: MEK

Summary: MEK1 and MEK2 inhibitor

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
A4004 NSC 632839 hydrochloride

Summary: Isopeptidases inhibitor

insoluble in H2O; insoluble in EtOH; ≥17 mg/mL
A4019 LY-411575

Summary: Gamma secretase inhibitor

≥23.85 mg/mL
A4057 AUY922 (NVP-AUY922)
1 Citation

Target: HSP90

Summary: Potent Hsp90 inhibitor

≥23.27 mg/mL