Ampicillin sodium
Catalog No.
A2510
β-lactam antibiotic
Featured Products
Ampicillin sodium (CAS 69-52-3) is a β-lactam antibiotic that exerts antibacterial activity by competitively inhibiting bacterial transpeptidase enzymes. Transpeptidases catalyze the critical final steps of bacterial cell wall biosynthesis; their inhibition disrupts cell-wall integrity, leading to bacterial cell lysis. In assays using E. coli 146 cells, ampicillin sodium demonstrates an IC50 value of 1.8 μg/ml against transpeptidase and an MIC value of 3.1 μg/ml. Research studies utilize ampicillin sodium to evaluate antibacterial efficacy in vitro and in animal infection models.
- 1. Molly E. Drosen, Sarojini Bulbule, et al. "Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord." Immunol Res. 2025 Jan 7;73(1):27 PMID: 39777574
- 2. Fuqiang Ma, Weiming Zhang, et al. "Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1β signalling pathway and gut-bone axis." Int Immunopharmacol. 2024 Aug 20:137:112472. PMID: 38897131
| Storage | Store at -20°C |
| M.Wt | 371.4 |
| Cas No. | 69-52-3 |
| Formula | C16H18N3NaO4S |
| Solubility | ≥18.57 mg/mL in H2O; ≥73.6 mg/mL in DMSO; ≥75.2 mg/mL in EtOH |
| Chemical Name | sodium;(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| SDF | Download SDF |
| Canonical SMILES | CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)[O-])C.[Na+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
