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Sivelestat sodium salt

In stock
Catalog No.
A4430
Leukocyte elastase inhibitor
Grouped product items
SizePriceStock Qty
5mg
$59.00
In stock
10mg
$106.00
In stock
25mg
$250.00
In stock
50mg
$442.00
In stock

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Background

Selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-κB activation and LTB4-induced neutrophil transmigration in vitro. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo.

Chemical Properties

Physical AppearanceWhite solid
StorageDesiccate at RT
M.Wt456.44
Cas No.150374-95-1
FormulaC20H21N2NaO7S
SolubilitySoluble in DMSO
Chemical Namesodium;2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate
SDFDownload SDF
Canonical SMILESCC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

Sivelestat sodium salt