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PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

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  1. Vinpocetine
    B2276 Vinpocetine
    Target: Phosphodiesterases (PDEs)
    Summary: PDE inhibitor
      ≥2.59 mg/mL
  2. Piclamilast
    B5630 Piclamilast
    Summary: PDE4 inhibitor
      <38.12 mg/mL
  3. TC-E 5005
    B5642 TC-E 5005
    Summary: PDE10A inhibitor
  4. Sildenafil mesylate
    B6073 Sildenafil mesylate
    Summary: PDE5 inhibitor
      ≥57.1 mg/mL
  5. Pimobendan hydrochloride
    B1165 Pimobendan hydrochloride
    Summary: Selective inhibitor of PDE3
      Soluble in DMSO
  6. Irsogladine
    B1593 Irsogladine
    Summary: PDE4 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥12.80 mg/mL
  7. Udenafil
    B3439 Udenafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; ≥117.2 mg/mL
  8. Ro 20-1724
    B6294 Ro 20-1724
    Summary: PDE4 inhibitor
      insoluble in H2O; ≥4.88 mg/mL
  9. Trequinsin hydrochloride
    B7022 Trequinsin hydrochloride
    Summary: PDE3 inhibitor
      Soluble in DMSO
  10. IBMX
    B7206 IBMX
     1 Citation
    Summary: Phosphodiesterase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.45 mg/mL

Items 1-10 of 55

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