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S- (+)-Rolipram

Catalog No.
A4349
CAMP-specific PDE4 inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$55.00
In stock
5mg
$50.00
In stock
10mg
$85.00
In stock
25mg
$190.00
In stock
50mg
$330.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

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Background

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt275.34
Cas No.85416-73-5
FormulaC16H21NO3
Solubility≥13.9 mg/mL in DMSO, ≥20.76 mg/mL in EtOH with ultrasonic and warming,insoluble in H2O
Chemical Name(4S)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one
SDFDownload SDF
Canonical SMILESCOC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

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