S- (+)-Rolipram
Catalog No.
A4349
CAMP-specific PDE4 inhibitor
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S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 275.34 |
| Cas No. | 85416-73-5 |
| Formula | C16H21NO3 |
| Solubility | insoluble in H2O; ≥13.9 mg/mL in DMSO; ≥20.76 mg/mL in EtOH with gentle warming and ultrasonic |
| Chemical Name | (4S)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one |
| SDF | Download SDF |
| Canonical SMILES | COc(ccc([C@H](C1)CNC1=O)c1)c1OC1CCCC1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
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