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PPY ABl kinases inhibitor

PPY A

Catalog No. A8607
Size Price Stock Qty
10mg $241.00 Ship Within 7 Days
50mg $1,018.00 Ship Within 7 Days

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

PPY A

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Chemical Properties

Cas No. 875634-01-8 SDF Download SDF
Chemical Name 5-[3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylpyridine-3-carboxamide
Canonical SMILES CN(C)C(=O)C1=CN=CC(=C1)C2=CN=C3C(=C2)C(=CN3)C4=CC=CC=C4OC
Formula C22H20N4O2 M.Wt 372.42
Solubility Soluble in DMSO > 10 mM Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

Potent inhibitor of T315l mutant and wild-type Abl kinases (IC50 values are 9 and 20 nM, respectively). Inhibits growth of cells transformed with either the Bcr-Abl T315l mutant or wild-type Bcr-Abl gene.