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MK-4827 hydrochloride

In stock
Catalog No.
B1163
PARP1/PARP2 inhibitor
Grouped product items
SizePriceStock Qty
5mg
$140.00
In stock
10mg
$234.00
In stock
50mg
$624.00
In stock
100mg
$1,014.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

MK-4827(Niraparib) Hcl is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.

Chemical Properties

StorageStore at -20°C
M.Wt356.85
Cas No.1038915-64-8
FormulaC19H21ClN4O
SolubilitySoluble in DMSO
Chemical Name2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide;hydrochloride
SDFDownload SDF
Canonical SMILESC1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N.Cl
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

MK-4827 hydrochloride